Instaflex Reviews-How Effective Is Instaflex for Joint Pains?

Today, one in four adults is dealing with some kind of joint issue. No wonder why the demand for joint supplements skyrocketed.  Due to this increased demand, the market is now full of supplements that …

Instaflex Reviews

Today, one in four adults is dealing with some kind of joint issue. No wonder why the demand for joint supplements skyrocketed. 

Due to this increased demand, the market is now full of supplements that contain filler ingredients.

Is Instaflex joint supplement one of them? Does it actually work?

Well, the majority of the Instaflex reviews show that this supplement does live up to the expectation. The ingredients it comes with are powerful and medically proven to improve joint issues. 

Whatever it is, if you’re confused about whether to go with Instaflex or not, this guide’s definitely going to help you. Check it out!

Dear Reader You Can Skip and Try Our Best Joint supplements List Here

Instaflex – Does it Actually Work?

The manufacturer claims that Instaflex can improve flexibility, mobility, help get rid of muscle stiffness, and gives joint pain relief within just 7 days. 

Anyone might doubt the credibility of this supplement by looking at the given time frame of 7 days.

Plus, there isn’t any strong evidence backing up that claim. So that’s something yet to find. Let’s keep the 7-day thing aside and take a look at the overall thing.

Is This Instaflex Supplement Really Effective for Treating Joint Issues? 

Several studies show that it is actually!

A study conducted by Appalachian State University shows that those people with knee pains who took Instaflex for a few weeks in a row have noticed around 37% reduction in joint pain.

In other studies, Instaflex has shown better performance than placebo pills as well. 

If we take a look at the ingredients this supplement packs in, it won’t be hard to believe that this thing actually works. 

It comes with turmeric, which is loaded with anti-inflammatory properties and antioxidants.  It’s the star ingredient of this supplement that is extremely effective in treating several joint issues.

The curcumin compound in turmeric is what does all the magic. 

Then there is Resveratrol which is another ingredient proven several times to be effective in treating OA (osteoarthritis) and RA (rheumatoid arthritis).

And then there is Boswellia Serrata Extract, which protects the joint from damage. 

Apart from these, there are some other ingredients too that offer numerous health benefits, and we’ll be looking into that shortly. 

Another thing about this supplement that is appreciated by many is its price.

It’s definitely not a cheap supplement, but compared to some other supplements, this one delivers better value for the bucks. 


  • Boswellia Serrata Extract protects the joint tissues from damage
  • Curcumin component in turmeric relieves joint pain and offers many health benefits
  • Turmeric suppresses cancer cells and might even treat some kinds of cancers
  • Resveratrol is effective in treating both osteoarthritis and rheumatoid arthritis
  • Black pepper extract increases the body’s ability to absorb nutrients better
  • Cellulose makes the bowel movement smooth and improves overall digestive health
  • It can improve mobility and joint elasticity 
  • Aids with inflammation
  • Ingredients in this supplement improve overall cardiovascular health


  • Instaflex supplement contains gelatin, therefore, it’s not suitable for vegetarians
  • The addition of chondroitin and glucosamine would’ve made this supplement more effective
  • Comes with a few filler ingredients 

What Are the Side Effects of Instaflex?

There are some side effects associated with this supplement, which are –

  • Nausea
  • Dizziness
  • Vomiting
  • Itching
  • Constipation
  • Headache
  • Indigestion
  • Itching
  • Edema

Some people might notice the above-mentioned issues in the initial stage, but these problems should be long gone within a week or two.

If you experience any of these issues or anything else for more than a week, make sure to consult with a doctor immediately. 

Who Can’t Take Instaflex?

  • If you’re pregnant or breastfeeding or have any kind of medical history, you should consult with a certified doctor before consuming any kind of supplement. 
  • Don’t take this supplement without consulting with a doctor if you’re on medicines. 
  • Since it contains gelatin, it’s not a suitable supplement for vegetarians.

Instaflex Ingredients and the Benefits It Offers

The following are some of the major ingredients that this Instaflex supplement brings to the table. Go through and know the health benefits they offer to understand the Instaflex mechanism better. 

Turmeric Extract (Rhizome) – 200 mg

This joint reliever contains 200 mg of turmeric extract, which delivers numerous health benefits, including relief from joint pains. 

Turmeric has been used as ayurvedic medicine for years, and recent studies show that it’s an incredible ingredient for joint pain. Since then, every top-notch joint pain supplement has included this ingredient.

It has various active ingredients, and curcumin is one of those. It’s loaded with antioxidant and anti-inflammatory properties, which aid with joint pain. 

To see if curcumin capsules work as well as other pain relievers, a trial has been conducted on a group of 139 people dealing with some kind of knee pain.

Half of them were given 500 mg curcumin capsules 3 times a day. The other half were given 50 mg of diclofenac (a non-steroidal anti-inflammatory drug for treating pain) twice a day. 

What researchers have found was curcumin capsules were effective, and the effect was the same as diclofenac. But what was impressive is patients better tolerated the curcumin capsules.

That indicates curcumin capsules can be used on people who’re intolerant to anti-inflammatory non-steroidal pills. 

According to a study conducted on a group of people over 40 years old with knee osteoarthritis showed a very positive result.

In that trial, curcumin capsules were compared with placebo pills, and curcumin capsules yielded admirable results. 

What Are the Other Health Benefits of Turmeric Extract?

  • Increases the overall antioxidant capacity of the body
  • Accelerates the BDNF brain hormone production
  • Improves overall cardiovascular health
  • It can prevent and might even treat cancer
  • It might help with Alzheimer’s diseases
  • Curcumin is effective in fighting off depression
  • Strengthens the immune system

Resveratrol – 100 mg

In OA (osteoarthritis) and RA’s (rheumatoid arthritis) premedical models, it’s found that Resveratrol packs some properties that can protect the joint from some damage. 

The breakdown of cartilage is one of the reasons behind joint pain, and several studies have shown that Resveratrol can protect the cartilage breakdown. 

Another test was conducted on a rabbit with arthritis, where the rabbit was injected with a dose of Resveratrol and showed positive effects. That being said, there is a big difference between taking a supplement orally and via injection. 

However, if we sum up most of the studies on Resveratrol, it’s fair to say that it has anti-inflammatory properties and can prevent joint damage.

Having that said, we’re still not clear about how effective only 100 mg of Resveratrol will be.

Since there are some medical studies that found it effective in pain relief when the minimum dosage was 150 mg.

What Are Other Health Benefits of Resveratrol?

  • It might inhibit cancer cell growth
  • Studies show it can increase the insulin sensitivity
  • Antioxidants and anti-inflammatory properties protect brain cells 
  • Can decrease the LDL cholesterol level
  • It might lower the blood pressure

Boswellia Serrata Extract – 100 mg

It’s also known as Indian frankincense, which is an herbal extract coming from the Boswellia Serrata tree. 

5-lox is an enzyme that is responsible for the breakdown of connective tissues around the joints. And acids in Boswellia Serrata extract prevent the growth of these enzymes, which results in improved joint health. 

There are many studies on this ingredient, and most of them agree that it can effectively treat osteoarthritis, rheumatoid arthritis, inflammatory bowel disease, and asthma. 

A study was conducted in 2003 where 30 people with osteoarthritis knee pain were given Boswellia Serrata extract for a few days in a row, and that actually reduced the pain. Furthermore, they noticed increased knee flexion too. 

Another study suggests that taking a high dosage of Boswellia Serrata Extract can improve overall physical activity. 

Some medical research shows that this ingredient might interfere with the autoimmune system, which might help with rheumatoid arthritis.

However­­­­­­, further studies are needed to back up this theory. 

What Are Other Health Benefits of Boswellia Serrata Extract?

  • It comes with properties that might prevent the cancer cell growth
  • It might decrease the symptoms of asthma
  • Anti-inflammatory properties in this ingredient make it effective for treating inflammatory bowel diseases

Black Pepper Extract – 5 mg

There is no direct link between black pepper extract or Bioperine to joint pain, according to many studies.

The reason why this ingredient is included in this supplement is it can increase the body’s ability to absorb the plant compound and nutrients.

One of the key ingredients in this supplement is turmeric. And studies show that Bioperine can make the body absorb the curcumin compound found in turmeric by 2000 percent.

Not only that, it helps the body absorb beta-carotene (a powerful compound for preventing the body’s cell damage) better as well.

Several studies show that Bioperine can accelerate brain functioning and can aid with treating Alzheimer’s disease too.

Moreover, it comes with some anti-inflammatory properties that keep chronic inflammation at the minimum level possible. 

What Are Other Health Benefits of Black Pepper Extract?

  • Can lower the LDL cholesterol level
  • Comes with properties that can help fight cancer
  • It might improve the overall blood sugar level
  • Loaded with antioxidants that improve the overall health


It’s an insoluble fiber that delivers numerous health benefits, but does it have any direct link with joint pain?

No! The reason why cellulose is included in this Instaflex supplement is to improve the overall digestive health of the consumer. 

Whether it’s Instaflex or any other supplement, initially they cause some minor side effects depending on people, the most common one is digestion issues. 

Cellulose accelerates the production of intestinal microflora, which is a species of bacteria that plays a major role in improving overall digestive health. 

What Are The Other Health Benefits of cellulose?

  • It makes bowel movement smooth
  • This fiber aids with weight management 
  • Reduces the chances of metabolic disorder
  • Maintains a cholesterol level
  • Manages the blood glucose level

Dosage Recommendation

The manufacturer recommends taking one capsule a day, which can be taken without food. The Instaflex supplement is designed for adults who’re not very physically active. It works best for people who do little to moderate physical activities. 

An Alternative Pick

Instaflexisn’t the only card in your hand when it comes down to effective supplements for joint pain, product Physio Flex Pro is also one of the top-rated supplements that are packed with powerful ingredients.

It comes with curcumin compound, which is found in turmeric and is medically proven to be extremely effective in treating arthritis, swelling, and different kinds of joint pains.

Turmeric also improves joint flexibility and mobility as well. 

Apart from that, it also comes with Resveratrol and Boswellia Serrata Extract, which can prevent joint tissue damage and give relief from joint pains.

Like these, there are some other ingredients that deliver a number of health benefits.

Frequently Asked Questions 

Does this supplement work on osteoarthritis on the shoulder and thumbs?

According to a few users, Instaflex supplements did give them relief from shoulder and thumb joint pains. Therefore, it’s fair to say that this supplement works in those areas too. 

Does it help with lower back pain?

Nope! Instaflex isn’t a supplement for back pains. There are supplements that are specifically designed for back pain, use one of them. 

How long does it take instaflex to work?

The manufacturer claims that it’s going to work within a week, though there isn’t any evidence proving this claim. But from users, what we can say is it might take two or three weeks to show any result. 

Is turmeric better than glucosamine?

Yes, turmeric does a better job of protecting the joints from damage compared to glucosamine. Curcumin compound in turmeric protects the joints from enzymes, oxidative stress, and inflammations. Whereas glucosamine only supports the connective tissues around the joints.


This is definitely not the best supplement for joints, but most of the Instaflex reviews indicate that users are happy with the performance of this supplement.

So, if you’ve any kind of joint issues, it might not be a bad idea to give it a try.

That being said, it’s always wise to consult with someone who’s experienced before deciding. 


Daily, J. W., Yang, M., & Park, S. (2016). Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Journal of Medicinal Food, 19(8), 717–729.

Paultre, K., Cade, W., Hernandez, D., Reynolds, J., Greif, D., & Best, T. (2021). Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: a systematic review. BMJ Open Sport & Exercise Medicine, 7(1), e000935.

Siddiqui, M. Z. (2011). Boswellia Serrata, A Potential Anti-inflammatory Agent: An Overview. Indian Journal of Pharmaceutical Sciences, 73(3), 255–261.

Bang, J. S., Oh, D. H., Choi, H. M., Sur, B.-J., Lim, S.-J., Kim, J. Y., … Kim, K. S. (2009). Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis Research & Therapy, 11(2), R49.

Nguyen, C., Savouret, J.-F., Widerak, M., Corvol, M.-T., & Rannou, F. (2017).Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review. Nutrients, 9(1), 45.

Dr. Matt Boold is a licensed clinical psychologist who conducts structured assessment and psychotherapy with medical patients and mental health consumers in Reno, Nevada. He also conducts original research on posttraumatic stress and emotional regulation in clinical disorders, and he teaches university courses on related topics.

Leave a Comment