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Megan Elizabeth Bowles Clowse, MD, and Mary F. Hebert, FCCP

Megan Elizabeth Bowles Clowse, MD is a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy. Since 2007, she has collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies. This registry includes clinical data, pregnancy outcomes, and a large sample repository. In collaboration with Duke Pediatric Cardiology, she found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus. Dr. Clowse has also conducted studies on vasculitis and ovarian function and pregnancy and she is the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, an online pregnancy registry for women with these rare conditions. Dr. Clowse is starting a study to identify causes for the high rate of infertility among women with rheumatoid arthritis. She is also working on several projects to better understand how psoriatic arthritis impacts pregnancy.

Mary F. Hebert, FCCP, is professor of pharmacy and adjunct professor of OBGYN, Director of the University of Washington Obstetric-Fetal Pharmacology Research Unit, core member of the UW Center for Ecogenetics and Environmental Health and member of the UW Institute of Translational Health Sciences. She is a fellow of the American College of Clinical Pharmacy. Dr. Hebert received her PharmD degree in 1987, completed a clinical pharmacy residency in 1988 and Fellowship in 1990 at the University of California, San Francisco. Dr. Hebert joined the UW faculty in 1996 after serving on the clinical faculty at the University of California, San Francisco for six years. She has 26 years of experience conducting clinical pharmacokinetic and pharmacodynamic trials resulting in 82 publications. She has been an invited speaker at many national and international conferences. Her research focuses on the pharmacokinetics and pharmacodynamics of immune modulators in solid organ transplantation and the clinical pharmacology of medications in pregnancy and lactation. Her current work in obstetric-fetal pharmacology focuses on the mechanistic basis for clinical pharmacology changes in medications of therapeutic value during pregnancy.